Trait impulsivity as an endophenotype for bipolar I disorder
نویسندگان
چکیده
منابع مشابه
Neurocognitive performance as an endophenotype for bipolar disorder.
Identification of the underlying liability to develop bipolar disorders (BD) is hindered by the genetic complexity and phenotypic heterogeneity of the disease. The use of endophenotypes has been acknowledged as a promising approach that may detect the hidden manifestations of a genetic liability for an illness. One of the most commonly proposed endophenotypes in BD is neurocognitive performance...
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BACKGROUND Neuroimaging investigations of white matter abnormalities in subjects at genetic risk for bipolar disorders (BD) potentially predating the onset of BD offer several advantages. They are not confounded by the presence of illness duration or previous treatment with medication and may ultimately inform evaluation of risk for subsequent development of BD and subsequent therapeutic interv...
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1professor of psychology, school of education, federal university of goiás and doctoral student of the post graduate program in neurosciences at the federal university of Minas gerais, Belo Horizonte, Brazil. 2professor of Mental Health department and psychiatry, federal university of Minas gerais, Belo Horizonte, Brazil. 3professor of Mental Health department and psychiatry, federal university...
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Impulsivity and sensation seeking are stimulus-oriented traits. Because they differ in degree of intention and planning, they may have distinct neurophysiological mechanisms. Impulsivity is prominent in bipolar disorder, and may be related to pre-attentional information filtering and stimulus-orientation. We investigated specificity of relationships between impulsivity and sensitivity to stimul...
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In the early twentieth century, it was reported that the rate of perceptual alternation of the Necker cube (shown in Fig. 1a) was slower in patients with manic depression than in patients with dementia praecox (1,2). Despite several subsequent studies of perceptual alternation rates in psychiatric groups [see (3)], these observations remained relatively obscure until, independently and serendip...
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ژورنال
عنوان ژورنال: Bipolar Disorders
سال: 2012
ISSN: 1398-5647
DOI: 10.1111/j.1399-5618.2012.01035.x